hrp0097p2-145 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Clinical observation of post-menarche in idiopathic central precocious puberty or rapidly progressive puberty treated by GnRHa and GnRHa+rhGH

Chen PingPing , Chen Linqi , Wu Haiying

Objective: To investigate the clinical efficacy of GnRHa in the treatment of girls with post-menarche in ICPP or rapidly progressive puberty(RPP). To analyze the effect of GnRHa combined with rhGH on growth velocity (GV) and predicted adult height (PAH) in the process of GnRHa treatment with too low growth velocity.Methods: Retrospective analysis of the clinical data of 55 post-menarche ICPP/RPP girls withi...

hrp0097p2-310 | Late Breaking | ESPE2023

Exploration of rapidly progressive puberty early prediction in girls

Chen Linqi , Chen PingPing

Objective: To explore the influencing factors of girls with rapidly progressive puberty(RPP), to construct a risk prediction model of RPP in girls, to investigate the value of serum IGFBP-2, Irisin and Ghrelin in prediction of RPP in girls.Methods: 1. Construction and verification of the prediction model for girls with rapidly progressive puberty. The girls who visited the Department of Endocrinology, Children's Hos...